Safety with Parathion
نویسندگان
چکیده
منابع مشابه
Methyl parathion comes inside.
Research Public health scientists are increasingly discovering that the recent emergence or re-emergence of infectious diseases has an origin in environmental change (McMichael and Martens 2002; Morse 1995; Patz et al. 2000). These environmental changes encompass social processes such as urbanization and creation of transportation infrastructure, as well as eco-logic processes such as land and ...
متن کاملChicago area methyl parathion response.
The Illinois Department of Public Health participated in the Chicago, Illinois, area methyl parathion (MP) response with several other federal, state, and local government agencies beginning in April 1997. This response was initiated on evidence that hundreds of homes in the Chicago area were illegally treated for cockroaches with MP over a period of several years. Through applicator receipt bo...
متن کاملMethyl Parathion and Parathion-induced Cyto-genotoxicity to Human Liver Carcinoma (hepg2) Cells via Oxidative Stress
Methyl parathion (C8H10NO5PS) and parathion (C10H14NO5PS) are both organophosphate insecticides (OPI) widely used for household and agricultural applications. They are known for their ability to irreversibly inhibit acetylcholinesterase which often leads to a profound effect on the nervous system of exposed organisms. Many recently published studies have indicated that human exposure to OPI may...
متن کاملIsolation of methyl parathion-degrading strain M6 and cloning of the methyl parathion hydrolase gene.
A degradative bacterium, M6, was isolated and presumptively identified as Plesiomonas sp. strain M6 was able to hydrolyze methyl parathion to p-nitrophenol. A novel organophosphate hydrolase gene designated mpd was selected from its genomic library prepared by shotgun cloning. The nucleotide sequence of the mpd gene was determined. The gene could be effectively expressed in Escherichia coli.
متن کاملBiotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
Studies in rat liver have shown that cytochrome P450 (CYP) enzymes mediate the oxidative biotransformation of the phosphorothioate pesticide parathion to paraoxon and 4-nitrophenol. Transfer of the phosphorothioate thionosulfur atom to the CYP apoprotein results in amino acid modification and enzyme inactivation. Our study investigated the role of human hepatic CYP in parathion oxidation and th...
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ژورنال
عنوان ژورنال: BMJ
سال: 1964
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5424.1593-c